85E Evaluation of the use of different insulin regimens in the treatment of type1 and type 2 diabetes mellitus

Wednesday, October 24, 2012
Westin Diplomat Resort
Maha Mahmoud Al Hakim, Master, in, Clinical, Pharmacy1, Abobakr Abasaeed, Pharm, D, in, Pharmacy2 and D.Jones Jones, Professor3
1Mafraq Hospital.Inpatient Pharmacy.Drug Information Centre.Abu Dhabi.UAE, Abu Dhabi, United Arab Emirates
2Ministry of Health, Abu Dhabi, United Arab Emirates
3Queen University .Belfast.Irland.UK, Belfast, United Kingdom

Purpose: To compare the effect of different insulin regimens and to evaluate patient satisfaction and acceptability of the regimens after a consistent high quality diabetic education program through a multidisciplinary team.

Methods:  Design Analysis of data collected from a randomized cross sectional study performed through retrospective and prospective phases. Data obtained though the qualitative and quantitative method. The data collected was analyzed using SPSS software, frequency distribution and cross tabulation. Setting: Endocrinology clinic and wards in Al Mafraq Hospital in the United Arab Emirates. The Hospital is well-equipped facility with 450 beds.   Sample: 120 male/female diabetic patients consist of 37 males and 53 females aged 18 years and older. These patients were randomly selected between April 2008 and June 2009. Interventions: Implementation of multidisciplinary diabetic education program.

Results: The analysis of data showed that the highest percentage of patients (41.6%) achieved the therapeutic goal (A1C <7%) were on basal bolus insulin (MDI), and mild hypoglycemia most frequently occurred (48.2%) in patients with this regimen too. In terms of educational intervention, the data demonstrated that the highest percentage of patients achieved glycemic goal corresponded to the "very good" response to learning education program. Regarding patient satisfaction with current insulin treatment, 50% of the "very satisfied" are on basal bolus insulin analogues.

Conclusion: This study goes in accordance with clinical studies suggesting that analogue regimens can be used successfully to achieve guidelines' target and the initiation and intensification of insulin is a vital part of the care plan for many patients with diabetes. The results showed that the highest percentage of the patients achieved target glycemia where treated by basal-bolus and it is the most preferred regimen by its users.  Effectively educate patients about their insulin therapy will improve glycemic control, and their compliance with insulin regimens through multidisciplinary diabetic team